• Western blot analysis of extracts of various cell lines, using IFNGR2 Rabbit polyclonal antibody (STJ116437) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-IFNGR2 antibody (221-322) (STJ116437)

SKU:
STJ116437

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Host: Rabbit
Applications: WB
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-IFNGR2 (221-322) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IFNGR2
Gene ID: 3460
Uniprot ID: INGR2_HUMAN
Immunogen Region: 221-322
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 221-322 of human IFNGR2 (NP_005525.2).
Immunogen Sequence: SNIFRVGHLSNISCYETMAD ASTELQQVILISVGTFSLLS VLAGACFFLVLKYRGLIKYW FHTPPSIPLQIEEYLKDPTQ PILEALDKDSSPKDDVWDSV SI
Tissue Specificity Expressed in T-cells (at protein level).
Function Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG). Ligand binding stimulates activation of the JAK/STAT signaling pathway. Required for signal transduction in contrast to other receptor subunit responsible for ligand binding.
Protein Name Interferon Gamma Receptor 2
Ifn-Gamma Receptor 2
Ifn-Gamma-R2
Interferon Gamma Receptor Accessory Factor 1
Af-1
Interferon Gamma Receptor Beta-Chain
Ifn-Gamma-R-Beta
Interferon Gamma Transducer 1
Database Links Reactome: R-HSA-877300
Reactome: R-HSA-877312
Reactome: R-HSA-9679191
Reactome: R-HSA-9732724
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cytoplasmic Vesicle Membrane
Golgi Apparatus Membrane
Endoplasmic Reticulum Membrane
Cytoplasm
Has Low Cell Surface Expression And High Cytoplasmic Expression In T Cells
The Bias Towards Cytoplasmic Expression May Be Due To Ligand-Independent Receptor Internalization And Recycling
Alternative Antibody Names Anti-Interferon Gamma Receptor 2 antibody
Anti-Ifn-Gamma Receptor 2 antibody
Anti-Ifn-Gamma-R2 antibody
Anti-Interferon Gamma Receptor Accessory Factor 1 antibody
Anti-Af-1 antibody
Anti-Interferon Gamma Receptor Beta-Chain antibody
Anti-Ifn-Gamma-R-Beta antibody
Anti-Interferon Gamma Transducer 1 antibody
Anti-IFNGR2 antibody
Anti-IFNGT1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance