Anti-IL17RB antibody

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Product name Anti-IL17RB antibody
Short Description Rabbit polyclonal against IL17RB
Description The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.
Applications WB
Dilution range WB 1:1000 - 1:4000
Protein Name Interleukin-17 Receptor B
Il-17 Receptor B
Il-17rb
Cytokine Receptor-Like 4
Il-17 Receptor Homolog 1
Il-17rh1
Il17rh1
Interleukin-17b Receptor
Il-17b Receptor
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 18-292 of human IL17RB (NP_061195. 2).
Storage Instruction Store at -20°C and avoid freeze-thaw cycles.
Note FOR RESEARCH USE ONLY (RUO).
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Gene ID 55540
Gene Symbol IL17RB
Molecular Weight Calculated: 31kDa/55kDa. Observed: 75kDa
Database Links Reactome: R-HSA-448424
Alternative Names Anti-Interleukin-17 Receptor B antibody
Anti-Il-17 Receptor B antibody
Anti-Il-17rb antibody
Anti-Cytokine Receptor-Like 4 antibody
Anti-Il-17 Receptor Homolog 1 antibody
Anti-Il-17rh1 antibody
Anti-Il17rh1 antibody
Anti-Interleukin-17b Receptor antibody
Anti-Il-17b Receptor antibody
Anti-IL17RB CRL4 EVI27 IL17BR UNQ2501/PRO19612 antibody
Function Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells.
Cellular Localization Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Secreted
Tissue Specificity Expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas, testis, colon, brain and small intestine.not detected in peripheral blood leukocytes, lymphoid organs, and most cell lines.
Swiss-Prot Key I17RB_HUMAN
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