Anti-IL17RB Antibody

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Product name Anti-IL17RB Antibody
Short Description Rabbit polyclonal against IL17RB
Description The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.
Applications WB
Dilution range WB 1:1000 - 1:4000
Protein Name Interleukin-17 receptor B
IL-17 receptor B
IL-17RB
Cytokine receptor-like 4
IL-17 receptor homolog 1
IL-17Rh1
IL17Rh1
Interleukin-17B receptor
IL-17B receptor
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 18-292 of human IL17RB (NP_061195.2).
Storage Instruction Store at -20C. Avoid freeze / thaw cycles.
Note For Research Use Only (RUO).
Validated Application WB
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene ID 55540
Gene Symbol IL17RB
Molecular Weight 55.885 kDa
Database Links HGNC:18015
OMIM:605458
Reactome:R-HSA-448424
Alternative Names Interleukin-17 receptor B
IL-17 receptor B
IL-17RB
Cytokine receptor-like 4
IL-17 receptor homolog 1
IL-17Rh1
IL17Rh1
Interleukin-17B receptor
IL-17B receptor
Function Receptor for the proinflammatory cytokines IL17B and IL17E, May play a role in controlling the growth and/or differentiation of hematopoietic cells,
Cellular Localization Cell membrane
Tissue Specificity Expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas, testis, colon, brain and small intestine
Swiss-Prot Key Q9NRM6
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