• Western blot analysis of extracts of various cell lines, using IL21R antibody (STJ29604) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-IL21R antibody (20-240) (STJ29604)

SKU:
STJ29604

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-IL21R (20-240) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IL21R
Gene ID: 50615
Uniprot ID: IL21R_HUMAN
Immunogen Region: 20-240
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-240 of human IL21R (NP_851565.4).
Immunogen Sequence: GVSMPRGWAAPLLLLLLQGG WGCPDLVCYTDYLQTVICIL EMWNLHPSTLTLTWQDQYEE LKDEATSCSLHRSAHNATHA TYTCHMDVFHFMADDIFSVN ITDQSGNYSQECGSFLLAES IKPAPPFNVTVTFSGQYNIS WRSDYEDPAFYMLKGKLQYE LQYRNRGDPWAVSPRRKLIS VDSRSVSLLPLEFRKDSSYE LQVRAGPMPGSSYQGTWSEW S
Tissue Specificity Selectively expressed in lymphoid tissues. Most highly expressed in thymus and spleen.
Post Translational Modifications C-mannosylated at Trp-214 in the WSXWS motif, the sugar chain makes extensive hydrogen bonds with Asn-73 sugar, and bridges the two fibronectin domains transforming the V-shaped receptor into an A-frame.
Function This is a receptor for interleukin-21.
Protein Name Interleukin-21 Receptor
Il-21 Receptor
Il-21r
Novel Interleukin Receptor
Cd Antigen Cd360
Database Links Reactome: R-HSA-9020958
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Interleukin-21 Receptor antibody
Anti-Il-21 Receptor antibody
Anti-Il-21r antibody
Anti-Novel Interleukin Receptor antibody
Anti-Cd Antigen Cd360 antibody
Anti-IL21R antibody
Anti-NILR antibody
Anti-UNQ3121 antibody
Anti-PRO10273 antibody

Information sourced from Uniprot.org

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