• Western blot analysis of extracts of mouse spleen, using CD127/IL7R antibody (STJ115463) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

Anti-IL7R antibody (21-239) (STJ115463)

SKU:
STJ115463

Shipping:
Free Shipping
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CD127 (21-239) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IL7R
Gene ID: 3575
Uniprot ID: IL7RA_HUMAN
Immunogen Region: 21-239
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-239 of human CD127/IL7R (NP_002176.2).
Immunogen Sequence: ESGYAQNGDLEDAELDDYSF SCYSQLEVNGSQHSLTCAFE DPDVNITNLEFEICGALVEV KCLNFRKLQEIYFIETKKFL LIGKSNICVKVGEKSLTCKK IDLTTIVKPEAPFDLSVVYR EGANDFVVTFNTSHLQKKYV KVLMHDVAYRQEKDENKWTH VNLSSTKLTLLQRKLQPAAM YEIKVRSIPDHYFKGFWSEW SPSYYFRTPEINNSSGEMD
Post Translational Modifications N-glycosylated IL-7Ralpha binds IL7 300-fold more tightly than the unglycosylated form.
Function Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).
Protein Name Interleukin-7 Receptor Subunit Alpha
Il-7 Receptor Subunit Alpha
Il-7r Subunit Alpha
Il-7r-Alpha
Il-7ra
Cdw127
Cd Antigen Cd127
Database Links Reactome: R-HSA-1266695
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 3: Cell Membrane
Isoform 4: Secreted
Alternative Antibody Names Anti-Interleukin-7 Receptor Subunit Alpha antibody
Anti-Il-7 Receptor Subunit Alpha antibody
Anti-Il-7r Subunit Alpha antibody
Anti-Il-7r-Alpha antibody
Anti-Il-7ra antibody
Anti-Cdw127 antibody
Anti-Cd Antigen Cd127 antibody
Anti-IL7R antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance