• Western blot analysis of extracts of various cell lines, using KCNK10 antibody (STJ113281) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-KCNK10 antibody (384-543) (STJ113281)

SKU:
STJ113281

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-KCNK10 (384-543) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KCNK10
Gene ID: 54207
Uniprot ID: KCNKA_HUMAN
Immunogen Region: 384-543
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 384-543 of human KCNK10 (NP_612191.1).
Immunogen Sequence: RLGLDQRAHSLDMLSPEKRS VFAALDTGRFKASSQESINN RPNNLRLKGPEQLNKHGQGA SEDNIINKFGSTSRLTKRKN KDLKKTLPEDVQKIYKTFRN YSLDEEKKEEETEKMCNSDN SSTAMLTDCIQQHAELENGM IPTDTKDREPENNSLLEDRN
Tissue Specificity Abundantly expressed in pancreas and kidney and to a lower level in brain, testis, colon, and small intestine. Isoform b is strongly expressed in kidney (primarily in the proximal tubule) and pancreas, whereas isoform c is abundantly expressed in brain.
Function Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents. Activated by arachidonic acid and other naturally occurring unsaturated free fatty acids.
Protein Name Potassium Channel Subfamily K Member 10
Outward Rectifying Potassium Channel Protein Trek-2
Trek-2 K(+ Channel Subunit
Database Links Reactome: R-HSA-1299503
Reactome: R-HSA-5576886
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Potassium Channel Subfamily K Member 10 antibody
Anti-Outward Rectifying Potassium Channel Protein Trek-2 antibody
Anti-Trek-2 K(+ Channel Subunit antibody
Anti-KCNK10 antibody
Anti-TREK2 antibody

Information sourced from Uniprot.org

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