• Western blot analysis of extracts of rat testis, using KCNU1 antibody (STJ117166) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-KCNU1 antibody (920-1149) (STJ117166)

SKU:
STJ117166

Shipping:
Free Shipping
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-KCNU1 (920-1149) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KCNU1
Gene ID: 157855
Uniprot ID: KCNU1_HUMAN
Immunogen Region: 920-1149
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 920-1149 of human KCNU1 (NP_001027006.2).
Immunogen Sequence: LELLQMLVTGGVSSQLEQHL DKDKVYGVADSCTSLLSGRN RCKLGLLSLHETILSDVNPR NTFGQLFCGSLDLFGILCVG LYRIIDEEELNPENKRFVIT RPANEFKLLPSDLVFCAIPF STACYKRNEEFSLQKSYEIV NKASQTTETHSDTNCPPTID SVTETLYSPVYSYQPRTNSL SFPKQIAWNQSRTNSIISSQ IPLGDNAKENERKTSDEVYD EDPFAYSEPL
Tissue Specificity Testis-specific.
Function Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). May represent the primary spermatozoan K(+) current. In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+). Critical for fertility. May play an important role in sperm osmoregulation required for the acquisition of normal morphology and motility when faced with osmotic challenges, such as those experienced after mixing with seminal fluid and entry into the vagina.
Protein Name Potassium Channel Subfamily U Member 1
Calcium-Activated Potassium Channel Subunit Alpha-3
Calcium-Activated Potassium Channel - Subfamily M Subunit Alpha-3
Kca5
Slowpoke Homolog 3
Database Links Reactome: R-HSA-1300642
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Potassium Channel Subfamily U Member 1 antibody
Anti-Calcium-Activated Potassium Channel Subunit Alpha-3 antibody
Anti-Calcium-Activated Potassium Channel - Subfamily M Subunit Alpha-3 antibody
Anti-Kca5 antibody
Anti-Slowpoke Homolog 3 antibody
Anti-KCNU1 antibody
Anti-KCNMA3 antibody
Anti-KCNMC1 antibody
Anti-SLO3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance