| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KIR2DL1 (22-270) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KIR2DL1 |
| Gene ID: |
3802 |
| Uniprot ID: |
KI2L1_HUMAN |
| Immunogen Region: |
22-270 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 22-270 of human KIR2DL1 (XP_003403624.1). |
| Immunogen Sequence: |
HEGVHRKPSLLAHPGRLVKS EETVILQCWSDVRFEHFLLH REGKFKDTLHLIGEHHDGVS KANFSIGPMMQDLAGTYRCY GSVTHSPYQLSAPSDPLDIV ITGLYEKPSLSAQPGPTVLA GESVTLSCSSRSSYDMYHLS REGEAHECRFSAGPKVNGTF QADFPLGPATHGGTYRCFGS FRDSPYEWSNSSDPLLVSVT GNPSNSWPSPTEPSSKTERM FHHVGQACLKLPTSSDPTV |
| Tissue Specificity | Expressed by NK cells. |
| Function | Receptor on natural killer (NK) cells for some HLA-C alleles such as w4 and w6. Inhibits the activity of NK cells thus preventing cell lysis. |
| Protein Name | Killer Cell Immunoglobulin-Like Receptor 2dl1Cd158 Antigen-Like Family Member ANatural Killer-Associated Transcript 1Nkat-1P58 Natural Killer Cell Receptor Clones Cl-42/47.11P58 Nk Receptor Cl-42/47.11P58.1 Mhc Class-I-Specific Nk ReceptorCd Antigen Cd158a |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Killer Cell Immunoglobulin-Like Receptor 2dl1 antibodyAnti-Cd158 Antigen-Like Family Member A antibodyAnti-Natural Killer-Associated Transcript 1 antibodyAnti-Nkat-1 antibodyAnti-P58 Natural Killer Cell Receptor Clones Cl-42/47.11 antibodyAnti-P58 Nk Receptor Cl-42/47.11 antibodyAnti-P58.1 Mhc Class-I-Specific Nk Receptor antibodyAnti-Cd Antigen Cd158a antibodyAnti-KIR2DL1 antibodyAnti-CD158A antibodyAnti-NKAT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
