Anti-LMO1 Antibody

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Product name Anti-LMO1 Antibody
Short Description Rabbit polyclonal against LMO1
Description This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions; thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Rhombotin-1
Cysteine-rich protein TTG-1
LIM domain only protein 1
LMO-1
T-cell translocation protein 1
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-156 of human LMO1 (NP_002306.1).
Storage Instruction Store at -20C. Avoid freeze / thaw cycles.
Note For Research Use Only (RUO).
Validated Application WB
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene ID 4004
Gene Symbol LMO1
Molecular Weight 17.828 kDa
Database Links HGNC:6641
OMIM:186921
Reactome:R-HSA-8939236
Alternative Names Rhombotin-1
Cysteine-rich protein TTG-1
LIM domain only protein 1
LMO-1
T-cell translocation protein 1
Function May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors,
Cellular Localization Nucleus
Tissue Specificity Expressed mainly in the central nervous, Low level of expression in other tissues including thymus
Swiss-Prot Key P25800
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