| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-LRIG1 (816-1093) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LRIG1 |
| Gene ID: |
26018 |
| Uniprot ID: |
LRIG1_HUMAN |
| Immunogen Region: |
816-1093 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 816-1093 of human LRIG1 (NP_056356.2). |
| Immunogen Sequence: |
YQTRKKSEEYSVTNTDETVV PPDVPSYLSSQGTLSDRQET VVRTEGGPQANGHIESNGVC PRDASHFPEPDTHSVACRQP KLCAGSAYHKEPWKAMEKAE GTPGPHKMEHGGRVVCSDCN TEVDCYSRGQAFHPQPVSRD SAQPSAPNGPEPGGSDQEHS PHHQCSRTAAGSCPECQGSL YPSNHDRMLTAVKKKPMASL DGKGDSSWTLARLYHPDSTE LQPASSLTSGSPERAEAQY |
| Tissue Specificity | Widely expressed. |
| Function | Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation. |
| Protein Name | Leucine-Rich Repeats And Immunoglobulin-Like Domains Protein 1Lig-1 |
| Database Links | Reactome: R-HSA-177929Reactome: R-HSA-6807004 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Leucine-Rich Repeats And Immunoglobulin-Like Domains Protein 1 antibodyAnti-Lig-1 antibodyAnti-LRIG1 antibodyAnti-LIG1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
