• Immunohistochemistry analysis of paraffin-embedded mouse stomach using LRRC59 Rabbit polyclonal antibody (STJ112062) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded human brain using LRRC59 Rabbit polyclonal antibody (STJ112062) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded rat cerebellum using LRRC59 Rabbit polyclonal antibody (STJ112062) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of extracts from wild type (WT) and LRRC59 knockout (KO) 293T (KO) cells, using LRRC59 antibody (STJ112062) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-LRRC59 antibody (1-244) (STJ112062)

SKU:
STJ112062

£212.50 - £501.50
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-LRRC59 (1-244) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LRRC59
Gene ID: 55379
Uniprot ID: LRC59_HUMAN
Immunogen Region: 1-244
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-244 of human LRRC59 (NP_060979.2).
Immunogen Sequence: MTKAGSKGGNLRDKLDGNEL DLSLSDLNEVPVKELAALPK ATILDLSCNKLTTLPSDFCG LTHLVKLDLSKNKLQQLPAD FGRLVNLQHLDLLNNKLVTL PVSFAQLKNLKWLDLKDNPL DPVLAKVAGDCLDEKQCKQC ANKVLQHMKAVQADQERERQ RRLEVEREAEKKREAKQRAK EAQERELRKREKAEEKERRR KEYDALKAAKREQEKKPKKE ANQAPKSKSGSRPRKPPPR
Tissue Specificity Widely expressed.
Function Required for nuclear import of FGF1, but not that of FGF2. Might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores.
Protein Name Leucine-Rich Repeat-Containing Protein 59
Ribosome-Binding Protein P34
P34 Cleaved Into - Leucine-Rich Repeat-Containing Protein 59 - N-Terminally Processed
Cellular Localisation Microsome Membrane
Single-Pass Type Ii Membrane Protein
Endoplasmic Reticulum Membrane
Nucleus Envelope
Localization In The Nuclear Envelope Depends Upon The Nuclear Import Machinery
Including Kpnb1
Alternative Antibody Names Anti-Leucine-Rich Repeat-Containing Protein 59 antibody
Anti-Ribosome-Binding Protein P34 antibody
Anti-P34 Cleaved Into - Leucine-Rich Repeat-Containing Protein 59 - N-Terminally Processed antibody
Anti-LRRC59 antibody
Anti-PRO1855 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance