• Western blot analysis of extracts of various cell lines, using LYPD3 antibody (STJ117073) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-LYPD3 antibody (31-326) (STJ117073)

SKU:
STJ117073

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-LYPD3 (31-326) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LYPD3
Gene ID: 27076
Uniprot ID: LYPD3_HUMAN
Immunogen Region: 31-326
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 31-326 of human LYPD3 (NP_055215.2).
Immunogen Sequence: LECYSCVQKADDGCSPNKMK TVKCAPGVDVCTEAVGAVET IHGQFSLAVRGCGSGLPGKN DRGLDLHGLLAFIQLQQCAQ DRCNAKLNLTSRALDPAGNE SAYPPNGVECYSCVGLSREA CQGTSPPVVSCYNASDHVYK GCFDGNVTLTAANVTVSLPV RGCVQDEFCTRDGVTGPGFT LSGSCCQGSRCNSDLRNKTY FSPRIPPLVRLPPPEPTTVA STTSVTTSTSAPVRPTSTT
Tissue Specificity Expressed in placenta, skin and urothelium. Found in suprabasal keratinocytes of chronic wounds. Weak expression is found in esophagus and peripheral blood mononuclear cells. Found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression is found in the tumor component of some noninvasive superficial lesions and in invasive and metastatic urothelial cancers.
Post Translational Modifications N-glycosylated and O-glycosylated.
Function Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression.
Protein Name Ly6/Plaur Domain-Containing Protein 3
Gpi-Anchored Metastasis-Associated Protein C4.4a Homolog
Matrigel-Induced Gene C4 Protein
Mig-C4
Database Links Reactome: R-HSA-163125
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Antibody Names Anti-Ly6/Plaur Domain-Containing Protein 3 antibody
Anti-Gpi-Anchored Metastasis-Associated Protein C4.4a Homolog antibody
Anti-Matrigel-Induced Gene C4 Protein antibody
Anti-Mig-C4 antibody
Anti-LYPD3 antibody
Anti-C4.4A antibody
Anti-UNQ491 antibody
Anti-PRO1007 antibody

Information sourced from Uniprot.org

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