| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MAT1A (1-395) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MAT1A |
| Gene ID: |
4143 |
| Uniprot ID: |
METK1_HUMAN |
| Immunogen Region: |
1-395 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-395 of human MAT1A (NP_000420.1). |
| Immunogen Sequence: |
MNGPVDGLCDHSLSEGVFMF TSESVGEGHPDKICDQISDA VLDAHLKQDPNAKVACETVC KTGMVLLCGEITSMAMVDYQ RVVRDTIKHIGYDDSAKGFD FKTCNVLVALEQQSPDIAQC VHLDRNEEDVGAGDQGLMFG YATDETEECMPLTIILAHKL NARMADLRRSGLLPWLRPDS KTQVTVQYMQDNGAVIPVRI HTIVISVQHNEDITLEEMRR ALKEQVIRAVVPAKYLDED |
| Tissue Specificity | Expressed in liver. |
| Post Translational Modifications | S-nitrosylation of Cys-120 inactivates the enzyme. An intrachain disulfide bond can be formed. The protein structure shows that the relevant Cys residues are in a position that would permit formation of a disulfide bond. |
| Function | Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate. |
| Protein Name | S-Adenosylmethionine Synthase Isoform Type-1Adomet Synthase 1Methionine Adenosyltransferase 1Mat 1Methionine Adenosyltransferase I/IiiMat-I/Iii |
| Database Links | Reactome: R-HSA-156581Reactome: R-HSA-1614635Reactome: R-HSA-2408508Reactome: R-HSA-5579024 |
| Alternative Antibody Names | Anti-S-Adenosylmethionine Synthase Isoform Type-1 antibodyAnti-Adomet Synthase 1 antibodyAnti-Methionine Adenosyltransferase 1 antibodyAnti-Mat 1 antibodyAnti-Methionine Adenosyltransferase I/Iii antibodyAnti-Mat-I/Iii antibodyAnti-MAT1A antibodyAnti-AMS1 antibodyAnti-MATA1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
