• Western blot analysis of extracts of various cell lines, using MC2R antibody (STJ24517) at 1:500 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.

Anti-MC2R antibody (1-100) (STJ24517)

SKU:
STJ24517

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MC2R (1-100) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MC2R
Gene ID: 4158
Uniprot ID: ACTHR_HUMAN
Immunogen Region: 1-100
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human MC2R (NP_000520.1)
Immunogen Sequence: MKHIINSYENINNTARNNSD CPRVVLPEEIFFTISIVGVL ENLIVLLAVFKNKNLQAPMY FFICSLAISDMLGSLYKILE NILIILRNMGYLKPRGSFET
Tissue Specificity Melanocytes and corticoadrenal tissue.
Function Receptor for corticotropin (ACTH). This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase (cAMP).
Protein Name Adrenocorticotropic Hormone Receptor
Acth Receptor
Acth-R
Adrenocorticotropin Receptor
Melanocortin Receptor 2
Mc2-R
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-418555
Reactome: R-HSA-5579031
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Adrenocorticotropic Hormone Receptor antibody
Anti-Acth Receptor antibody
Anti-Acth-R antibody
Anti-Adrenocorticotropin Receptor antibody
Anti-Melanocortin Receptor 2 antibody
Anti-Mc2-R antibody
Anti-MC2R antibody
Anti-ACTHR antibody

Information sourced from Uniprot.org

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