• Western blot analysis of extracts of various cell lines, using NFASC antibody (STJ24750) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-NFASC antibody (830-1100) (STJ24750)

SKU:
STJ24750

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-NFASC (830-1100) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NFASC
Gene ID: 23114
Uniprot ID: NFASC_HUMAN
Immunogen Region: 830-1100
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 830-1100 of human NFASC (NP_001005388.2).
Immunogen Sequence: RFRVRQPNLETINLEWDHPE HPNGIMIGYTLKYVAFNGTK VGKQIVENFSPNQTKFTVQR TDPVSRYRFTLSARTQVGSG EAVTEESPAPPNEATPTAAP PTLPPTTVGATGAVSSTDAT AIAATTEATTVPIIPTVAPT TIATTTTVATTTTTTAAATT TTESPPTTTSGTKIHESAPD EQSIWNVTVLPNSKWANITW KHNFGPGTDFVVEYIDSNHT KKTVPVKAQAQPIQLTDLY
Function Cell adhesion, ankyrin-binding protein which may be involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell interactions.
Protein Name Neurofascin
Database Links Reactome: R-HSA-445095
Reactome: R-HSA-447043
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 8: Cell Junction
Paranodal Septate Junction
Alternative Antibody Names Anti-Neurofascin antibody
Anti-NFASC antibody
Anti-KIAA0756 antibody

Information sourced from Uniprot.org

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