• Western blot analysis of extracts of various cell lines, using P2RX2 antibody (STJ29158) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-P2RX2 antibody (60-320) (STJ29158)

SKU:
STJ29158

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-P2RX2 (60-320) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: P2RX2
Gene ID: 22953
Uniprot ID: P2RX2_HUMAN
Immunogen Region: 60-320
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 60-320 of human P2RX2 (NP_733782.1).
Immunogen Sequence: VFIVQKSYQESETGPESSII TKVKGITTSEHKVWDVEEYV KPPEGGSVFSIITRVEATHS QTQGTCPESIRVHNATCLSD ADCVAGELDMLGNGLRTGRC VPYYQGPSKTCEVFGWCPVE DGASVSQFLGTMAPNFTILI KNSIHYPKFHFSKGNIADRT DGYLKRCTFHEASDLYCPIF KLGFIVEKAGESFTELAHKG GVIGVIINWDCDLDLPASEC NPKYSFRRLDPKHVPASSG
Function Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle.
Protein Name P2x Purinoceptor 2
P2x2
Atp Receptor
Purinergic Receptor
Database Links Reactome: R-HSA-139853
Reactome: R-HSA-418346
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Localizes To The Apical Membranes Of Hair Cells In The Organ Of Corti
Alternative Antibody Names Anti-P2x Purinoceptor 2 antibody
Anti-P2x2 antibody
Anti-Atp Receptor antibody
Anti-Purinergic Receptor antibody
Anti-P2RX2 antibody
Anti-P2X2 antibody

Information sourced from Uniprot.org

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