• Western blot analysis of extracts from 293 cells, using Phospho-MARCKS-S162 antibody (STJ22280). Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% BSA.
  • Immunofluorescence analysis of methanol-fixed HeLa cells using Phospho-MARCKS-S162 antibody (STJ22280).

Anti-Phospho-MARCKS-S162 antibody (STJ22280)

SKU:
STJ22280

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-MARCKS-S162 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:100-1:500
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MARCKS
Gene ID: 4082
Uniprot ID: MARCS_HUMAN
Immunogen: A phospho specific peptide corresponding to residues surrounding S162 of human MARCKS
Immunogen Sequence: Email for sequence
Post Translational Modifications Phosphorylation by PKC displaces MARCKS from the membrane. It also inhibits the F-actin cross-linking activity.
Function MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein.
Protein Name Myristoylated Alanine-Rich C-Kinase Substrate
Marcks
Protein Kinase C Substrate - 80 Kda Protein - Light Chain
80k-L Protein
Pkcsl
Database Links Reactome: R-HSA-399997
Cellular Localisation Cytoplasm
Cytoskeleton
Membrane
Lipid-Anchor
Alternative Antibody Names Anti-Myristoylated Alanine-Rich C-Kinase Substrate antibody
Anti-Marcks antibody
Anti-Protein Kinase C Substrate - 80 Kda Protein - Light Chain antibody
Anti-80k-L Protein antibody
Anti-Pkcsl antibody
Anti-MARCKS antibody
Anti-MACS antibody
Anti-PRKCSL antibody

Information sourced from Uniprot.org

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