| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PLOD1 (488-727) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PLOD1 |
| Gene ID: |
5351 |
| Uniprot ID: |
PLOD1_HUMAN |
| Immunogen Region: |
488-727 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 488-727 of human PLOD1 (NP_000293.2). |
| Immunogen Sequence: |
RQQDVFMFLTNRHTLGHLLS LDSYRTTHLHNDLWEVFSNP EDWKEKYIHQNYTKALAGKL VETPCPDVYWFPIFTEVACD ELVEEMEHFGQWSLGNNKDN RIQGGYENVPTIDIHMNQIG FEREWHKFLLEYIAPMTEKL YPGYYTRAQFDLAFVVRYKP DEQPSLMPHHDASTFTINIA LNRVGVDYEGGGCRFLRYNC SIRAPRKGWTLMHPGRLTHY HEGLPTTRGTRYIAVSFVD |
| Function | Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils. Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links (Probable). |
| Protein Name | Procollagen-Lysine -2-Oxoglutarate 5-Dioxygenase 1Lysyl Hydroxylase 1Lh1 |
| Database Links | Reactome: R-HSA-1650814 |
| Cellular Localisation | Rough Endoplasmic Reticulum MembranePeripheral Membrane ProteinLumenal Side |
| Alternative Antibody Names | Anti-Procollagen-Lysine -2-Oxoglutarate 5-Dioxygenase 1 antibodyAnti-Lysyl Hydroxylase 1 antibodyAnti-Lh1 antibodyAnti-PLOD1 antibodyAnti-LLH antibodyAnti-PLOD antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
