| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PPFIA3 (460-590) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PPFIA3 |
| Gene ID: |
8541 |
| Uniprot ID: |
LIPA3_HUMAN |
| Immunogen Region: |
460-590 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 460-590 of human PPFIA3 (NP_003651.1). |
| Immunogen Sequence: |
NSLSEEIANMKKLQDELLLN KEQLLAEMERMQMEIDQLRG RPPSSYSRSLPGSALELRYS QAPTLPSGAHLDPYVAGSGR AGKRGRWSGVKEEPSKDWER SAPAGSIPPPFPGELDGSDE EEAEGMFGAEL |
| Tissue Specificity | Predominantly expressed in brain. Also detected in sperm (at protein level). |
| Function | May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. |
| Protein Name | Liprin-Alpha-3Protein Tyrosine Phosphatase Receptor Type F Polypeptide-Interacting Protein Alpha-3Ptprf-Interacting Protein Alpha-3 |
| Database Links | Reactome: R-HSA-181429Reactome: R-HSA-181430Reactome: R-HSA-210500Reactome: R-HSA-212676Reactome: R-HSA-264642Reactome: R-HSA-388844 |
| Cellular Localisation | CytoplasmCytoplasmic VesicleSecretory VesicleAcrosomeAlso Detected In Epididymosome |
| Alternative Antibody Names | Anti-Liprin-Alpha-3 antibodyAnti-Protein Tyrosine Phosphatase Receptor Type F Polypeptide-Interacting Protein Alpha-3 antibodyAnti-Ptprf-Interacting Protein Alpha-3 antibodyAnti-PPFIA3 antibodyAnti-KIAA0654 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
