| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PPP3CC (373-512) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PPP3CC |
| Gene ID: |
5533 |
| Uniprot ID: |
PP2BC_HUMAN |
| Immunogen Region: |
373-512 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 373-512 of human PPP3CC (NP_005596.2). |
| Immunogen Sequence: |
LISDDEAEGSTTVRKEIIRN KIRAIGKMARVFSILRQESE SVLTLKGLTPTGTLPLGVLS GGKQTIETATVEAVEAREAI RGFSLQHKIRSFEEARGLDR INERMPPRKDSIHAGGPMKS VTSAHSHAAHRSDQGKKAHS |
| Tissue Specificity | Testis. |
| Function | Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca(2+)-mediated signals. Dephosphorylates and activates transcription factor NFATC1. Dephosphorylates and inactivates transcription factor ELK1. Dephosphorylates DARPP32. |
| Protein Name | Serine/Threonine-Protein Phosphatase 2b Catalytic Subunit Gamma IsoformCam-Prp Catalytic SubunitCalcineurin - Testis-Specific Catalytic SubunitCalmodulin-Dependent Calcineurin A Subunit Gamma Isoform |
| Database Links | Reactome: R-HSA-111447Reactome: R-HSA-180024 |
| Cellular Localisation | MitochondrionLocalizes In The Mitochondria In A Spata33-Dependent Manner |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Phosphatase 2b Catalytic Subunit Gamma Isoform antibodyAnti-Cam-Prp Catalytic Subunit antibodyAnti-Calcineurin - Testis-Specific Catalytic Subunit antibodyAnti-Calmodulin-Dependent Calcineurin A Subunit Gamma Isoform antibodyAnti-PPP3CC antibodyAnti-CALNA3 antibodyAnti-CNA3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
