| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PRDM2 (1-176) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PRDM2 |
| Gene ID: |
7799 |
| Uniprot ID: |
PRDM2_HUMAN |
| Immunogen Region: |
1-176 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-176 of human PRDM2 (NP_036363.2). |
| Immunogen Sequence: |
MNQNTTEPVAATETLAEVPE HVLRGLPEEVRLFPSAVDKT RIGVWATKPILKGKKFGPFV GDKKKRSQVKNNVYMWEVYY PNLGWMCIDATDPEKGNWLR YVNWACSGEEQNLFPLEINR AIYYKTLKPIAPGEELLVWY NGEDNPEIAAAIEEERASAR SKRSSPKSRKGKKKSQ |
| Tissue Specificity | Highly expressed in retinoblastoma cell lines and in brain tumors. Also expressed in a number of other cell lines and in brain, heart, skeletal muscle, liver and spleen. Isoform 1 is expressed in testis at much higher level than isoform 3. |
| Function | S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3. May function as a DNA-binding transcription factor. Binds to the macrophage-specific TPA-responsive element (MTE) of the HMOX1 (heme oxygenase 1) gene and may act as a transcriptional activator of this gene. |
| Protein Name | Pr Domain Zinc Finger Protein 2Gata-3-Binding Protein G3bLysine N-Methyltransferase 8Mtb-ZfMte-Binding ProteinPr Domain-Containing Protein 2Retinoblastoma Protein-Interacting Zinc Finger ProteinZinc Finger Protein Riz |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Pr Domain Zinc Finger Protein 2 antibodyAnti-Gata-3-Binding Protein G3b antibodyAnti-Lysine N-Methyltransferase 8 antibodyAnti-Mtb-Zf antibodyAnti-Mte-Binding Protein antibodyAnti-Pr Domain-Containing Protein 2 antibodyAnti-Retinoblastoma Protein-Interacting Zinc Finger Protein antibodyAnti-Zinc Finger Protein Riz antibodyAnti-PRDM2 antibodyAnti-KMT8 antibodyAnti-RIZ antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
