Anti-PTPRD antibody

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Anti-PTPRD antibody

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Product name Anti-PTPRD antibody
Short Description Rabbit polyclonal against PTPRD
Description Unconjugated Rabbit polyclonal to PTPRD
Applications ELISA, WB
Dilution range WB 1:500-2000
ELISA 1:5000-20000
Specificity PTPRD polyclonal antibody detects endogenous levels of protein.
Protein Name Receptor-Type Tyrosine-Protein Phosphatase Delta
Protein-Tyrosine Phosphatase Delta
R-Ptp-Delta
Immunogen Synthesized peptide derived from human PTPRD protein.
Immunogen Region 510-590aa
Storage Instruction Store at-20°C, and avoid repeat freeze-thaw cycles.
Note FOR RESEARCH USE ONLY (RUO).
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse
Conjugation Unconjugated
Concentration 1 mg/ml
Purification PTPRD antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene ID 5789
Gene Symbol PTPRD
Molecular Weight 210 kDa
Database Links HGNC:9668
OMIM:601598
Alternative Names Anti-Receptor-Type Tyrosine-Protein Phosphatase Delta antibody
Anti-Protein-Tyrosine Phosphatase Delta antibody
Anti-R-Ptp-Delta antibody
Anti-PTPRD antibody
Function Can bidirectionally induce pre-and post-synaptic differentiation of neurons by mediating interaction with IL1RAP and IL1RAPL1 trans-synaptically. Involved in pre-synaptic differentiation through interaction with SLITRK2.
Post-translational Modifications A cleavage occurs, separating the extracellular domain from the transmembrane segment. This process called 'ectodomain shedding' is thought to be involved in receptor desensitization, signal transduction and/or membrane localization.
Cellular Localization Membrane
Single-Pass Type I Membrane Protein
Swiss-Prot Key PTPRD_HUMAN
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