• Western blot analysis of lysates from mouse liver, using PTPRK Rabbit polyclonal antibody (STJ116973) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 60s.

Anti-PTPRK antibody (600-750) (STJ116973)

SKU:
STJ116973

£169.50 - £449.50
Shipping:
Free Shipping
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PTPRK (600-750) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PTPRK
Gene ID: 5796
Uniprot ID: PTPRK_HUMAN
Immunogen Region: 600-750
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 600-750 of human PTPRK (NP_001129120.1).
Immunogen Sequence: EGVDASLNETATTITVLLRP AQAKGAPISAYQIVVEELHP HRTKREAGAMECYQVPVTYQ NAMSGGAPYYFAAELPPGNL PEPAPFTVGDNRTYQGFWNP PLAPRKGYNIYFQAMSSVEK ETKTQCVRIATKAAATEEPE VIPDPAKQTDR
Tissue Specificity High levels in lung, brain and colon.less in liver, pancreas, stomach, kidney, placenta and mammary carcinoma.
Post Translational Modifications This protein undergoes proteolytic processing.
Function Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Negative regulator of EGFR signaling pathway. Forms complexes with beta-catenin and gamma-catenin/plakoglobin. Beta-catenin may be a substrate for the catalytic activity of PTPRK/PTP-kappa.
Protein Name Receptor-Type Tyrosine-Protein Phosphatase Kappa
Protein-Tyrosine Phosphatase Kappa
R-Ptp-Kappa
Database Links Reactome: R-HSA-182971
Cellular Localisation Cell Junction
Adherens Junction
Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Receptor-Type Tyrosine-Protein Phosphatase Kappa antibody
Anti-Protein-Tyrosine Phosphatase Kappa antibody
Anti-R-Ptp-Kappa antibody
Anti-PTPRK antibody
Anti-PTPK antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance