• Western blot analysis of extracts of HT-29 cells, using PTPRO Antibody (STJ29038) at 1:1000 dilution. _Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. _Lysates/proteins: 25ug per lane. _Blocking buffer: 3% nonfat dry milk in TBST. _Detection: ECL Enhanced Kit. _Exposure time: 30s.

Anti-PTPRO antibody (30-300) (STJ29038)

SKU:
STJ29038

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Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PTPRO (30-300) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PTPRO
Gene ID: 5800
Uniprot ID: PTPRO_HUMAN
Immunogen Region: 30-300
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-300 of human PTPRO (NP_109592.1).
Immunogen Sequence: FHVTVQDDNNIVVSLEASDV ISPASVYVVKITGESKNYFF EFEEFNSTLPPPVIFKASYH GLYYIITLVVVNGNVVTKPS RSITVLTKPLPVTSVSIYDY KPSPETGVLFEIHYPEKYNV FTRVNISYWEGKDFRTMLYK DFFKGKTVFNHWLPGMCYSN ITFQLVSEATFNKSTLVEYS GVSHEPKQHRTAPYPPQNIS VRIVNLNKNNWEEQSGNFPE ESFMRSQDTIGKEKLFHFT
Tissue Specificity Glomerulus of kidney. Also detected in brain, lung and placenta.
Function Possesses tyrosine phosphatase activity. Plays a role in regulating the glomerular pressure/filtration rate relationship through an effect on podocyte structure and function.
Protein Name Receptor-Type Tyrosine-Protein Phosphatase O
R-Ptp-O
Glomerular Epithelial Protein 1
Protein Tyrosine Phosphatase U2
Ptp-U2
Ptpase U2
Database Links Reactome: R-HSA-9034015
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Receptor-Type Tyrosine-Protein Phosphatase O antibody
Anti-R-Ptp-O antibody
Anti-Glomerular Epithelial Protein 1 antibody
Anti-Protein Tyrosine Phosphatase U2 antibody
Anti-Ptp-U2 antibody
Anti-Ptpase U2 antibody
Anti-PTPRO antibody
Anti-GLEPP1 antibody
Anti-PTPU2 antibody

Information sourced from Uniprot.org

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