| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PXK (1-200) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PXK |
| Gene ID: |
54899 |
| Uniprot ID: |
PXK_HUMAN |
| Immunogen Region: |
1-200 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PXK (NP_060241.2). |
| Immunogen Sequence: |
MAFMEKPPAGKVLLDDTVPL TAAIEASQSLQSHTEYIIRV QRGISVENSWQIVRRYSDFD LLNNSLQIAGLSLPLPPKKL IGNMDREFIAERQKGLQNYL NVITTNHILSNCELVKKFLD PNNYSANYTEIALQQVSMFF RSEPKWEVVEPLKDIGWRIR KKYFLMKIKNQPKERLVLSW ADLGPDKYLSDKDFQCLIKL |
| Tissue Specificity | Widely expressed in all tissues examined except in heart. Isoform 1 is expressed in high levels in the brain, skeletal muscle, spleen and testis. Isoform 7 expression has yet to be demonstrated. |
| Function | Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity. |
| Protein Name | Px Domain-Containing Protein Kinase-Like ProteinModulator Of -K-AtpaseMonaka |
| Cellular Localisation | CytoplasmCell MembranePeripheral Membrane ProteinAlso Associates With The Plasma MembraneIsoform 3 Is Present Throughout The Cell |
| Alternative Antibody Names | Anti-Px Domain-Containing Protein Kinase-Like Protein antibodyAnti-Modulator Of -K-Atpase antibodyAnti-Monaka antibodyAnti-PXK antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
