• Western blot analysis of various lysates using QSOX2 Rabbit polyclonal antibody (STJ117408) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-QSOX2 antibody (370-650) (STJ117408)

SKU:
STJ117408

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Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-QSOX2 (370-650) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: QSOX2
Gene ID: 169714
Uniprot ID: QSOX2_HUMAN
Immunogen Region: 370-650
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 370-650 of human QSOX2 (NP_859052.3).
Immunogen Sequence: VKKLLEMLQEWLASLPLDRI PYNAVLDLVNNKMRISGIFL TNHIKWVGCQGSRSELRGYP CSLWKLFHTLTVEASTHPDA LVGTGFEDDPQAVLQTMRRY VHTFFGCKECGEHFEEMAKE SMDSVKTPDQAILWLWKKHN MVNGRLAGHLSEDPRFPKLQ WPTPDLCPACHEEIKGLASW DEGHVLTFLKQHYGRDNLLD TYSADQGDSSEGGTLARGEE EEKRLTPPEVSHGDRDTQS
Tissue Specificity Expressed in pancreas, brain, placenta, kidney, heart and fetal tissues. Weakly expressed in lung, liver and skeletal muscles.
Function Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. Also seems to play a role in regulating the sensitization of neuroblastoma cells for interferon-gamma-induced apoptosis.
Protein Name Sulfhydryl Oxidase 2
Neuroblastoma-Derived Sulfhydryl Oxidase
Quiescin Q6-Like Protein 1
Cellular Localisation Membrane
Single-Pass Membrane Protein
Secreted
Cell Membrane
Nucleus Membrane
Seems To Be Predominantly Targeted To The Nuclear And Outer Plasma Membrane
Alternative Antibody Names Anti-Sulfhydryl Oxidase 2 antibody
Anti-Neuroblastoma-Derived Sulfhydryl Oxidase antibody
Anti-Quiescin Q6-Like Protein 1 antibody
Anti-QSOX2 antibody
Anti-QSCN6L1 antibody
Anti-SOXN antibody

Information sourced from Uniprot.org

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