• Western blot analysis of extracts of mouse brain, using RAB6A Antibody (STJ113986) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-RAB6A antibody (1-200) (STJ113986)

SKU:
STJ113986

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Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-RAB6A (1-200) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RAB6A
Gene ID: 5870
Uniprot ID: RAB6A_HUMAN
Immunogen Region: 1-200
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human RAB6A (NP_002860.2).
Immunogen Sequence: MSTGGDFGNPLRKFKLVFLG EQSVGKTSLITRFMYDSFDN TYQATIGIDFLSKTMYLEDR TIRLQLWDTAGQERFRSLIP SYIRDSAAAVVVYDITNVNS FQQTTKWIDDVRTERGSDVI IMLVGNKTDLADKRQVSIEE GERKAKELNVMFIETSAKAG YNVKQLFRRVAAALPGMEST QDRSREDMIDIKLEKPQEQP
Tissue Specificity Ubiquitous.
Post Translational Modifications Prenylated.
Function Regulator of COPI-independent retrograde transport from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity. Recruits VPS13B to the Golgi membrane. Plays a role in neuron projection development (Probable).
Protein Name Ras-Related Protein Rab-6a
Rab-6
Database Links Reactome: R-HSA-1912420
Reactome: R-HSA-6798695
Reactome: R-HSA-6811436
Reactome: R-HSA-6811440
Reactome: R-HSA-8854214
Reactome: R-HSA-8873719
Reactome: R-HSA-8876198
Cellular Localisation Golgi Apparatus Membrane
Lipid-Anchor
Cytoplasmic Vesicle
Secretory Vesicle
Acrosome Membrane
Peripheral Membrane Protein
Bicd2 Facilitates Its Targeting To Golgi Apparatus Membrane
Isoform 1: Golgi Apparatus Membrane
Isoform 2: Golgi Apparatus Membrane
Alternative Antibody Names Anti-Ras-Related Protein Rab-6a antibody
Anti-Rab-6 antibody
Anti-RAB6A antibody
Anti-RAB6 antibody

Information sourced from Uniprot.org

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