• Western blot analysis of extracts of various cell lines, using RNPC3 antibody (STJ28255) at 1:1000 dilution. _Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. _Lysates/proteins: 25ug per lane. _Blocking buffer: 3% nonfat dry milk in TBST. _Detection: ECL Enhanced Kit. _Exposure time: 60s.

Anti-RNPC3 antibody (258-517) (STJ28255)

SKU:
STJ28255

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-RNPC3 (258-517) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RNPC3
Gene ID: 55599
Uniprot ID: RNPC3_HUMAN
Immunogen Region: 258-517
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 258-517 of human RNPC3 (NP_060089.1).
Immunogen Sequence: NKLMELANLQPKRPKTIKQR HVRKKRKIKDMLNTPLCPSH SSLHPVLLPSDVFDQPQPVG NKRIEFHISTDMPAAFKKDL EKEQNCEEKNHDLPATEVDA SNIGFGKIFPKPNLDITEEI KEDSDEMPSECISRRELEKG RISREEMETLSVFRSYEPGE PNCRIYVKNLAKHVQEKDLK YIFGRYVDFSSETQRIMFDI RLMKEGRMKGQAFIGLPNEK AAAKALKEANGYVLFGKPM
Tissue Specificity Highly expressed in pancreas and kidney. Detected at lower levels in heart, brain, placenta, lung, liver, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes.
Function Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1% of all non-coding sequences. Binds to the 3'-stem-loop of m(7)G-capped U12 snRNA.
Protein Name Rna-Binding Region-Containing Protein 3
Rna-Binding Motif Protein 40
Rna-Binding Protein 40
U11/U12 Small Nuclear Ribonucleoprotein 65 Kda Protein
U11/U12 Snrnp 65 Kda Protein
U11/U12-65k
Database Links Reactome: R-HSA-72165
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Rna-Binding Region-Containing Protein 3 antibody
Anti-Rna-Binding Motif Protein 40 antibody
Anti-Rna-Binding Protein 40 antibody
Anti-U11/U12 Small Nuclear Ribonucleoprotein 65 Kda Protein antibody
Anti-U11/U12 Snrnp 65 Kda Protein antibody
Anti-U11/U12-65k antibody
Anti-RNPC3 antibody
Anti-KIAA1839 antibody
Anti-RBM40 antibody
Anti-RNP antibody
Anti-SNRNP65 antibody

Information sourced from Uniprot.org

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