• Immunofluorescence analysis of L929 cells using RPS19BP1 Rabbit polyclonal antibody (STJ115197) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Western blot analysis of various lysates using RPS19BP1 Rabbit polyclonal antibody (STJ115197) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-RPS19BP1 antibody (1-136) (STJ115197)

SKU:
STJ115197

£169.50 - £449.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-RPS19BP1 (1-136) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RPS19BP1
Gene ID: 91582
Uniprot ID: AROS_HUMAN
Immunogen Region: 1-136
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-136 of human RPS19BP1 (NP_919307.1).
Immunogen Sequence: MSAALLRRGLELLAASEAPR DPPGQAKPRGAPVKRPRKTK AIQAQKLRNSAKGKVPKSAL DEYRKRECRDHLRVNLKFLT RTRSTVAESVSQQILRQNRG RKACDRPVAKTKKKKAEGTV FTEEDFQKFQQEYFGS
Tissue Specificity Widely expressed (at protein level).
Post Translational Modifications Citrullinated by PADI4.
Function Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Acts as a chaperone that specifically mediates the integration of RPS19 in state post-A1. Direct regulator of SIRT1. Enhances SIRT1-mediated deacetylation of p53/TP53, thereby participating in inhibition of p53/TP53-mediated transcriptional activity.
Protein Name Active Regulator Of Sirt1
40s Ribosomal Protein S19-Binding Protein 1
Rps19-Binding Protein 1
S19bp
Database Links Reactome: R-HSA-3371453
Cellular Localisation Nucleus
Nucleolus
Alternative Antibody Names Anti-Active Regulator Of Sirt1 antibody
Anti-40s Ribosomal Protein S19-Binding Protein 1 antibody
Anti-Rps19-Binding Protein 1 antibody
Anti-S19bp antibody
Anti-RPS19BP1 antibody
Anti-AROS antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance