| Host: |
Rabbit |
| Applications: |
WB/IHC/IP |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SAMM50 (1-220) is suitable for use in Western Blot, Immunohistochemistry and Immunoprecipitation research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200IP 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SAMM50 |
| Gene ID: |
25813 |
| Uniprot ID: |
SAM50_HUMAN |
| Immunogen Region: |
1-220 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SAMM50 (NP_056195.3). |
| Immunogen Sequence: |
MGTVHARSLEPLPSSGPDFG GLGEEAEFVEVEPEAKQEIL ENKDVVVQHVHFDGLGRTKD DIIICEIGDVFKAKNLIEVM RKSHEAREKLLRLGIFRQVD VLIDTCQGDDALPNGLDVTF EVTELRRLTGSYNTMVGNNE GSMVLGLKLPNLLGRAEKVT FQFSYGTKETSYGLSFFKPR PGNFERNFSVNLYKVTGQFP WSSLRETDRGMSAEYSFPIW |
| Function | Plays a crucial role in the maintenance of the structure of mitochondrial cristae and the proper assembly of the mitochondrial respiratory chain complexes. Required for the assembly of TOMM40 into the TOM complex. |
| Protein Name | Sorting And Assembly Machinery Component 50 HomologTransformation-Related Gene 3 ProteinTrg-3 |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-8949613Reactome: R-HSA-9013404 |
| Cellular Localisation | Mitochondrion Outer MembraneMulti-Pass Membrane ProteinCytoplasmMitochondrion |
| Alternative Antibody Names | Anti-Sorting And Assembly Machinery Component 50 Homolog antibodyAnti-Transformation-Related Gene 3 Protein antibodyAnti-Trg-3 antibodyAnti-SAMM50 antibodyAnti-SAM50 antibodyAnti-CGI-51 antibodyAnti-TRG3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and Emerin/Emerin/EMD knockout (KO) 293T cells, using [KO Validated] Emerin/EMD Rabbit polyclonal antibody (STJ119989) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/98774/382822/STJ119989_1__22320.1713151321.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and Emerin/Emerin/EMD knockout (KO) 293T cells, using [KO Validated] Emerin/EMD Rabbit polyclonal antibody (STJ119989) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")