Anti-SDHA antibody

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Product name Anti-SDHA antibody
Description Rabbit polyclonal to SDHA.
Applications ELISA, WB
Dilution range WB 1:500-1:2000
ELISA 1:10000
Specificity SDHA Polyclonal Antibody detects endogenous levels of SDHA protein.
Protein Name Succinate dehydrogenase
ubiquinone flavoprotein subunit, mitochondrial
Flavoprotein subunit of complex II
Immunogen Synthesized peptide derived from human SDHA.
Immunogen Region C-terminal
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Validated Application WB
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 6389
Gene Symbol SDHA
Molecular Weight 72 kDa
Database Links HGNC:10680
Alternative Names Succinate dehydrogenase antibody
ubiquinone flavoprotein subunit, mitochondrial antibody
Flavoprotein subunit of complex II antibody
Fp antibody
SDH2 antibody
SDHF antibody
Function Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) . Can act as a tumor suppressor .
Post-translational Modifications Phosphorylation at Tyr-215 is important for efficient electron transfer in complex II and the prevention of ROS generation. Acetylated. Deacetylated by SIRT3.
Cellular Localization Mitochondrion inner membrane
Swiss-Prot Key P31040_HUMAN
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