• Immunohistochemistry analysis of SIVA1 in paraffin-embedded Human testis tissue using SIVA1 Rabbit polyclonal antibody (STJ28248) at a dilution of 1:200 (40x lens). High pressure antigen retrieval was performed with 0. 01 M citrate buffer (pH 6. 0) prior to immunohistochemistry staining.
  • Immunohistochemistry analysis of SIVA1 in paraffin-embedded Mouse Intestine tissue using SIVA1 Rabbit polyclonal antibody (STJ28248) at a dilution of 1:200 (40x lens). High pressure antigen retrieval was performed with 0. 01 M citrate buffer (pH 6. 0) prior to immunohistochemistry staining.
  • Western blot analysis of various lysates using SIVA1 Rabbit polyclonal antibody (STJ28248) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-SIVA1 antibody (1-110) (STJ28248)

SKU:
STJ28248

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SIVA1 (1-110) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SIVA1
Gene ID: 10572
Uniprot ID: SIVA_HUMAN
Immunogen Region: 1-110
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human SIVA1 (NP_068355.1).
Immunogen Sequence: MPKRSCPFADVAPLQLKVRV SQRELSRGVCAERYSQEVFD PSGVASIACSSCVRAVDGKA VCGQCERALCGQCVRTCWGC GSVACTLCGLVDCSDMYEKV LCTSCAMFET
Tissue Specificity Ubiquitous. Mostly expressed in thymus, testis, ovary, prostate, small intestine and spleen and less in colon.
Post Translational Modifications Phosphorylated by ABL2/ARG in response to oxidative stress.
Function Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.
Protein Name Apoptosis Regulatory Protein Siva
Cd27-Binding Protein
Cd27bp
Cellular Localisation Cytoplasm
Nucleus
In The Nucleus
Accumulates In Dot-Like Structures
Alternative Antibody Names Anti-Apoptosis Regulatory Protein Siva antibody
Anti-Cd27-Binding Protein antibody
Anti-Cd27bp antibody
Anti-SIVA1 antibody
Anti-SIVA antibody

Information sourced from Uniprot.org

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