| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SKIL (350-450) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SKIL |
| Gene ID: |
6498 |
| Uniprot ID: |
SKIL_HUMAN |
| Immunogen Region: |
350-450 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human SKIL (NP_005405.2). |
| Immunogen Sequence: |
EMKEKFSMRSGKRNQSKTDA PSGMELQSWYPVIKQEGDHV SQTHSFLHPSYYLYMCDKVV APNVSLTSAVSQSKELTKTE ASKSISRQSEKAHSSGKLQK T |
| Tissue Specificity | Isoform SNON and isoform SNOA are widely expressed. Highest expression is found in skeletal muscle, followed by placenta and lung. Lowest expression in heart, brain and pancreas. Isoform SNOI expression is restricted to skeletal muscle. |
| Post Translational Modifications | Ubiquitinated by RNF111 and ARK2C, promoting proteasomal degradation, leading to enhance the BMP-Smad signaling. |
| Function | May have regulatory role in cell division or differentiation in response to extracellular signals. |
| Protein Name | Ski-Like ProteinSki-Related OncogeneSki-Related Protein |
| Database Links | Reactome: R-HSA-2173795 |
| Alternative Antibody Names | Anti-Ski-Like Protein antibodyAnti-Ski-Related Oncogene antibodyAnti-Ski-Related Protein antibodyAnti-SKIL antibodyAnti-SNO antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
