| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC25A24 (1-200) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC25A24 |
| Gene ID: |
29957 |
| Uniprot ID: |
SCMC1_HUMAN |
| Immunogen Region: |
1-200 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human SLC25A24 (NP_037518.3). |
| Immunogen Sequence: |
MLRWLRDFVLPTAACQDAEQ PTRYETLFQALDRNGDGVVD IGELQEGLRNLGIPLGQDAE EKIFTTGDVNKDGKLDFEEF MKYLKDHEKKMKLAFKSLDK NNDGKIEASEIVQSLQTLGL TISEQQAELILQSIDVDGTM TVDWNEWRDYFLFNPVTDIE EIIRFWKHSTGIDIGDSLTI PDEFTEDEKKSGQWWRQLLA |
| Tissue Specificity | Expressed in all tissues tested. Highly expressed in testis, expressed at intermediate level in small intestine and pancreas, and weakly expressed in kidney, spleen, liver, skeletal muscle and heart. |
| Function | Electroneutral antiporter that mediates the transport of adenyl nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter. By regulating the mitochondrial matrix adenyl nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways. In vitro, a low activity is also observed with guanyl and pyrimidine nucleotides. May play a role in protecting cells against oxidative stress-induced cell death, by buffering calcium levels in the mitochondrial matrix through the formation of calcium-phosphate precipitates. |
| Protein Name | Mitochondrial Adenyl Nucleotide Antiporter Slc25a24Mitochondrial Atp-Mg/Pi Carrier Protein 1Mitochondrial Ca(2+-Dependent Solute Carrier Protein 1Short Calcium-Binding Mitochondrial Carrier Protein 1Scamc-1Solute Carrier Family 25 Member 24 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Adenyl Nucleotide Antiporter Slc25a24 antibodyAnti-Mitochondrial Atp-Mg/Pi Carrier Protein 1 antibodyAnti-Mitochondrial Ca(2+-Dependent Solute Carrier Protein 1 antibodyAnti-Short Calcium-Binding Mitochondrial Carrier Protein 1 antibodyAnti-Scamc-1 antibodyAnti-Solute Carrier Family 25 Member 24 antibodyAnti-SLC25A24 antibodyAnti-APC1 antibodyAnti-MCSC1 antibodyAnti-SCAMC1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
