• Western blot analysis of extracts of mouse heart, using SLURP1 antibody (STJ29203) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-SLURP1 antibody (1-103) (STJ29203)

SKU:
STJ29203

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Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SLURP1 (1-103) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLURP1
Gene ID: 57152
Uniprot ID: SLUR1_HUMAN
Immunogen Region: 1-103
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-103 of human SLURP1 (NP_065160.1).
Immunogen Sequence: MASRWAVQLLLVAAWSMGCG EALKCYTCKEPMTSASCRTI TRCKPEDTACMTTLVTVEAE YPFNQSPVVTRSCSSSCVAT DPDSIGAAHLIFCCFRDLCN SEL
Tissue Specificity Granulocytes. Expressed in skin. Predominantly expressed in the granular layer of skin, notably the acrosyringium. Identified in several biological fluids such as sweat, saliva, tears, plasma and urine.
Function Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. In vitro down-regulates keratinocyte proliferation.the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner. In T cells may be involved in regulation of intracellular Ca(2+) signaling. Seems to have an immunomodulatory function in the cornea. The function may implicate a possible role as a scavenger receptor for PLAU thereby blocking PLAU-dependent functions of PLAUR such as in cell migration and proliferation.
Protein Name Secreted Ly-6/Upar-Related Protein 1
Slurp-1
Ars Component B
Ars(Component B-81/S
Anti-Neoplastic Urinary Protein
Anup
Cellular Localisation Secreted
Alternative Antibody Names Anti-Secreted Ly-6/Upar-Related Protein 1 antibody
Anti-Slurp-1 antibody
Anti-Ars Component B antibody
Anti-Ars(Component B-81/S antibody
Anti-Anti-Neoplastic Urinary Protein antibody
Anti-Anup antibody
Anti-SLURP1 antibody
Anti-ARS antibody

Information sourced from Uniprot.org

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