• Western blot analysis of extracts of various cell lines, using SPATA7 antibody (STJ116497) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-SPATA7 antibody (300-599) (STJ116497)

SKU:
STJ116497

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SPATA7 (300-599) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SPATA7
Gene ID: 55812
Uniprot ID: SPAT7_HUMAN
Immunogen Region: 300-599
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 300-599 of human SPATA7 (NP_060888.2).
Immunogen Sequence: MNIKQASNCVTYDAKEKIAP LPLEGHDSTWDEIKDDALQH SSPRAMCQYSLKPPSTRKIY SDEEELLYLSFIEDVTDEIL KLGLFSNRFLERLFERHIKQ NKHLEEEKMRHLLHVLKVDL GCTSEENSVKQNDVDMLNVF DFEKAGNSEPNELKNESEVT IQQERQQYQKALDMLLSAPK DENEIFPSPTEFFMPIYKSK HSEGVIIQQVNDETNLETST LDENHPSISDSLTDRETSV
Function Involved in the maintenance of both rod and cone photoreceptor cells. It is required for recruitment and proper localization of RPGRIP1 to the photoreceptor connecting cilium (CC), as well as photoreceptor-specific localization of proximal CC proteins at the distal CC. Maintenance of protein localization at the photoreceptor-specific distal CC is essential for normal microtubule stability and to prevent photoreceptor degeneration.
Protein Name Spermatogenesis-Associated Protein 7
Hsd-3.1
Spermatogenesis-Associated Protein Hsd3
Cellular Localisation Cytoplasm
Cytoskeleton
Cilium Axoneme
Cilium Basal Body
Cell Projection
Cilium
Photoreceptor Outer Segment
Localizes To The Microtubule Network
Alternative Antibody Names Anti-Spermatogenesis-Associated Protein 7 antibody
Anti-Hsd-3.1 antibody
Anti-Spermatogenesis-Associated Protein Hsd3 antibody
Anti-SPATA7 antibody
Anti-HSD3 antibody

Information sourced from Uniprot.org

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