| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SRPX2 (166-465) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SRPX2 |
| Gene ID: |
27286 |
| Uniprot ID: |
SRPX2_HUMAN |
| Immunogen Region: |
166-465 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 166-465 of human SRPX2 (NP_055282.1). |
| Immunogen Sequence: |
DGRWSGGEPVCVDIDPPKIR CPHSREKMAEPEKLTARVYW DPPLVKDSADGTITRVTLRG PEPGSHFPEGEHVIRYTAYD RAYNRASCKFIVKVQVRRCP TLKPPQHGYLTCTSAGDNYG ATCEYHCDGGYDRQGTPSRV CQSSRQWSGSPPICAPMKIN VNVNSAAGLLDQFYEKQRLL IISAPDPSNRYYKMQISMLQ QSTCGLDLRHVTIIELVGQP PQEVGRIREQQLSANIIEE |
| Tissue Specificity | Expressed in neurons of the rolandic area of the brain (at protein level). Highly expressed in the brain, placenta, lung, trachea, uterus, adrenal gland, heart, ovary and placenta. Weakly expressed in the peripheral blood, brain and bone marrow. Expressed in numerous cancer cell lines and in gastrointestinal cancer cells. Higher levels found in colorectal cancers than in normal colonic mucosa. |
| Post Translational Modifications | Contains chondroitin sulfate chains. |
| Function | Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. May have a role in the perisylvian region, critical for language and cognitive development. |
| Protein Name | Sushi Repeat-Containing Protein Srpx2Sushi-Repeat Protein Upregulated In Leukemia |
| Cellular Localisation | SecretedCytoplasmCell SurfaceSynapse |
| Alternative Antibody Names | Anti-Sushi Repeat-Containing Protein Srpx2 antibodyAnti-Sushi-Repeat Protein Upregulated In Leukemia antibodyAnti-SRPX2 antibodyAnti-SRPUL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
