Anti-SRSF3 Antibody

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Product name Anti-SRSF3 Antibody
Short Description Rabbit polyclonal against SRSF3
Description The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants, one protein-coding and the other non-coding, have been found for this gene.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Serine/arginine-rich splicing factor 3
Pre-mRNA-splicing factor SRP20
Splicing factor
arginine/serine-rich 3
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human SRSF3 (NP_003008.1).
Storage Instruction Store at -20C. Avoid freeze / thaw cycles.
Note For Research Use Only (RUO).
Validated Application WB
Host Rabbit
Clonality Polyclonal
Reactivity Hamster, Human, Mouse, Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene ID 6428
Gene Symbol SRSF3
Molecular Weight 19.33 kDa
Database Links HGNC:10785
OMIM:603364
Reactome:R-HSA-109688
Alternative Names Serine/arginine-rich splicing factor 3
Pre-mRNA-splicing factor SRP20
Splicing factor
arginine/serine-rich 3
Function Splicing factor that specifically promotes exon-inclusion during alternative splicing ,
Post-translational Modifications Phosphorylated by CLK1, CLK2, CLK3 and CLK4, Extensively phosphorylated on serine residues in the RS domain,
Cellular Localization Nucleus
Swiss-Prot Key P84103
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