Anti-SYP antibody

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Product name Anti-SYP antibody
Short Description Rabbit monoclonal against SYP
Description This antibody recognizes a protein of 38kDa, identified as synaptophysin. It labels normal neuroendocrine cells of human adrenal medulla, carotid body, skin, pituitary gland, thyroid, lung, pancreas, gastrointestinal mucosa, Paneth’s cells the gastrointestinal tract and of gastric parietal cells. Neurons in the brain, spinal cord, and retina are labeled. In combination with anti-chromogranin and anti-NSE, Ab to synaptophysin is very useful the identification of normal neuroendocrine cells neuroendocrine neoplasms.
Applications IHC
Dilution range 1:100-200
Protein Name Synaptophysin
Major synaptic vesicle protein p38
Immunogen A synthetic peptide of human synaptophysin
Storage Instruction Store at 2-8°C for up to 1 year
Note For Research Use Only (RUO).
Validated Application IHC
Host Rabbit
Clonality Monoclonal
Reactivity Human
Conjugation Unconjugated
Isotype IgG
Formulation Tissue culture supernatant with 0.2% BSA and 15mM sodium azide.
Gene ID 6855
Gene Symbol SYP
Molecular Weight 34 kDa
Database Links HGNC:11506
Alternative Names Synaptophysin
Major synaptic vesicle protein p38
Function Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane, Involved in the regulation of short-term and long-term synaptic plasticity (By similarity),
Post-translational Modifications Ubiquitinated.
Cellular Localization Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane
Tissue Specificity Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.
Swiss-Prot Key P08247
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