• Western blot analysis of extracts of various cell lines, using TACR2 antibody (STJ25768) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-TACR2 antibody (319-398) (STJ25768)

SKU:
STJ25768

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TACR2 (319-398) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TACR2
Gene ID: 6865
Uniprot ID: NK2R_HUMAN
Immunogen Region: 319-398
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 319-398 of human TACR2 (NP_001048.2).
Immunogen Sequence: RLAFRCCPWVTPTKEDKLEL TPTTSLSTRVNRCHTKETLF MAGDTAPSEATSGEAGRPQD GSGLWFGYGLLAPTKTHVEI
Function This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.
Protein Name Substance-K Receptor
Skr
Nk-2 Receptor
Nk-2r
Neurokinin A Receptor
Tachykinin Receptor 2
Database Links Reactome: R-HSA-380095
Reactome: R-HSA-416476
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Substance-K Receptor antibody
Anti-Skr antibody
Anti-Nk-2 Receptor antibody
Anti-Nk-2r antibody
Anti-Neurokinin A Receptor antibody
Anti-Tachykinin Receptor 2 antibody
Anti-TACR2 antibody
Anti-NK2R antibody
Anti-NKNAR antibody
Anti-TAC2R antibody

Information sourced from Uniprot.org

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