Anti-TBPL1 Antibody

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Product name Anti-TBPL1 Antibody
Short Description Rabbit polyclonal against TBPL1
Description This gene encodes a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. The encoded protein does not bind to the TATA box and initiates transcription from TATA-less promoters. This gene plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.
Applications IF, WB
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:200
Protein Name TATA box-binding protein-like protein 1
TBP-like protein 1
21 kDa TBP-like protein
Second TBP of unique DNA protein
STUD
TATA box-binding protein-related factor 2
TBP-related factor 2
TBP-like factor
TBP-rel
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-186 of human TBPL1 (NP_004856.1).
Storage Instruction Store at -20C. Avoid freeze / thaw cycles.
Note For Research Use Only (RUO).
Validated Application WB IF
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene ID 9519
Gene Symbol TBPL1
Molecular Weight 20.887 kDa
Database Links HGNC:11589
OMIM:605521
Alternative Names TATA box-binding protein-like protein 1
TBP-like protein 1
21 kDa TBP-like protein
Second TBP of unique DNA protein
STUD
TATA box-binding protein-related factor 2
TBP-related factor 2
TBP-like factor
TBP-rel
Function Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter element at these genes, Seems to also mediate the transcription of NF1, Does not bind the TATA box,
Cellular Localization Cytoplasm
Tissue Specificity Ubiquitously expressed, with highest levels in the testis and ovary
Swiss-Prot Key P62380
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