| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TFCP2 (1-280) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TFCP2 |
| Gene ID: |
7024 |
| Uniprot ID: |
TFCP2_HUMAN |
| Immunogen Region: |
1-280 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TFCP2 (NP_005644.2). |
| Immunogen Sequence: |
MAWALKLPLADEVIESGLVQ DFDASLSGIGQELGAGAYSM SDVLALPIFKQEESSLPPDN ENKILPFQYVLCAATSPAVK LHDETLTYLNQGQSYEIRML DNRKLGELPEINGKLVKSIF RVVFHDRRLQYTEHQQLEGW RWNRPGDRILDIDIPMSVGI IDPRANPTQLNTVEFLWDPA KRTSVFIQVHCISTEFTMRK HGGEKGVPFRVQIDTFKENE NGEYTEHLHSASCQIKVFK |
| Tissue Specificity | Ubiquitous. Expressed in brain, ovary, kidney, thymus, spleen, liver, adrenal, heart and lung (at protein level). |
| Function | Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1. Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter. |
| Protein Name | Alpha-Globin Transcription Factor Cp2Saa3 Enhancer FactorTranscription Factor Lsf |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Alpha-Globin Transcription Factor Cp2 antibodyAnti-Saa3 Enhancer Factor antibodyAnti-Transcription Factor Lsf antibodyAnti-TFCP2 antibodyAnti-LSF antibodyAnti-SEF antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
