• Western blot analysis of extracts of mouse pancreas, using THRB antibody (STJ25847) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
  • Immunofluorescence analysis of U-2 OS cells using THRB antibody (STJ25847) at dilution of 1:100. Blue: DAPI for nuclear staining.

Anti-THRB antibody (1-263) (STJ25847)

SKU:
STJ25847

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-THRB (1-263) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: THRB
Gene ID: 7068
Uniprot ID: THB_HUMAN
Immunogen Region: 1-263
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-263 of human TR Beta 1/THRB (NP_000452.2).
Immunogen Sequence: MTPNSMTENGLTAWDKPKHC PDREHDWKLVGMSEACLHRK SHSERRSTLKNEQSSPHLIQ TTWTSSIFHLDHDDVNDQSV SSAQTFQTEEKKCKGYIPSY LDKDELCVVCGDKATGYHYR CITCEGCKGFFRRTIQKNLH PSYSCKYEGKCVIDKVTRNQ CQECRFKKCIYVGMATDLVL DDSKRLAKRKLIEENREKRR REELQKSIGHKPEPTDEEWE LIKTVTEAHVATNAQGSHW
Function Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
Protein Name Thyroid Hormone Receptor Beta
Nuclear Receptor Subfamily 1 Group A Member 2
C-Erba-2
C-Erba-Beta
Database Links Reactome: R-HSA-383280
Reactome: R-HSA-4090294
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Thyroid Hormone Receptor Beta antibody
Anti-Nuclear Receptor Subfamily 1 Group A Member 2 antibody
Anti-C-Erba-2 antibody
Anti-C-Erba-Beta antibody
Anti-THRB antibody
Anti-ERBA2 antibody
Anti-NR1A2 antibody
Anti-THR1 antibody

Information sourced from Uniprot.org

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