Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-TMEM55A (130-195) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:200-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PIP4P2 |
Gene ID: |
55529 |
Uniprot ID: |
PP4P2_HUMAN |
Immunogen Region: |
130-195 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 130-195 of human TMEM55A (NP_061180.1). |
Immunogen Sequence: |
VMLISEEQPAQPALPIQPEG TRVVCGHCGNTFLWMELRFN TLAKCPHCKKISSVGSALPR RRCCAY |
Tissue Specificity | Ubiquitous. |
Function | Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4-bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3-monophosphate. Negatively regulates the phagocytosis of large particles by reducing phagosomal phosphatidylinositol 4,5-bisphosphate accumulation during cup formation. |
Protein Name | Type 2 Phosphatidylinositol 4 -5-Bisphosphate 4-PhosphataseType 2 Ptdins-4 -5-P2 4-PtasePtdins-4 -5-P2 4-Ptase IiTransmembrane Protein 55a |
Cellular Localisation | Late Endosome MembraneMulti-Pass Membrane ProteinLysosome MembraneCytoplasmic VesiclePhagosome MembraneCell Membrane |
Alternative Antibody Names | Anti-Type 2 Phosphatidylinositol 4 -5-Bisphosphate 4-Phosphatase antibodyAnti-Type 2 Ptdins-4 -5-P2 4-Ptase antibodyAnti-Ptdins-4 -5-P2 4-Ptase Ii antibodyAnti-Transmembrane Protein 55a antibodyAnti-PIP4P2 antibodyAnti-TMEM55A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance