• Western blot analysis of lysates from mouse liver, using TMEM55A Rabbit polyclonal antibody (STJ117666) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 5s.

Anti-TMEM55A antibody (130-195) (STJ117666)

SKU:
STJ117666

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Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TMEM55A (130-195) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PIP4P2
Gene ID: 55529
Uniprot ID: PP4P2_HUMAN
Immunogen Region: 130-195
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 130-195 of human TMEM55A (NP_061180.1).
Immunogen Sequence: VMLISEEQPAQPALPIQPEG TRVVCGHCGNTFLWMELRFN TLAKCPHCKKISSVGSALPR RRCCAY
Tissue Specificity Ubiquitous.
Function Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4-bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3-monophosphate. Negatively regulates the phagocytosis of large particles by reducing phagosomal phosphatidylinositol 4,5-bisphosphate accumulation during cup formation.
Protein Name Type 2 Phosphatidylinositol 4 -5-Bisphosphate 4-Phosphatase
Type 2 Ptdins-4 -5-P2 4-Ptase
Ptdins-4 -5-P2 4-Ptase Ii
Transmembrane Protein 55a
Cellular Localisation Late Endosome Membrane
Multi-Pass Membrane Protein
Lysosome Membrane
Cytoplasmic Vesicle
Phagosome Membrane
Cell Membrane
Alternative Antibody Names Anti-Type 2 Phosphatidylinositol 4 -5-Bisphosphate 4-Phosphatase antibody
Anti-Type 2 Ptdins-4 -5-P2 4-Ptase antibody
Anti-Ptdins-4 -5-P2 4-Ptase Ii antibody
Anti-Transmembrane Protein 55a antibody
Anti-PIP4P2 antibody
Anti-TMEM55A antibody

Information sourced from Uniprot.org

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