| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TMEM70 (161-260) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TMEM70 |
| Gene ID: |
54968 |
| Uniprot ID: |
TMM70_HUMAN |
| Immunogen Region: |
161-260 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 161-260 of human TMEM70 (NP_060336.3). |
| Immunogen Sequence: |
FITKGYVIRLYHEATTDTYK AITYNAMLAETSTVFHQNDV KIPDAKHVFTTFYAKTKSLL VNPVLFPNREDYIHLMGYDK EEFILYMEETSEEKRHKDDK |
| Tissue Specificity | Lower expressed in the heart than in the liver (at protein level). |
| Function | Scaffold protein that participates in the c-ring assembly of mitochondrial ATP synthase (F(1)F(0) ATP synthase or complex V) by facilitating the membrane insertion and oligomer formation of the subunit c/ATP5MC1 through its interaction. Therefore, participates in the early stage of mitochondrial ATP synthase biogenesis and also protects subunit c/ATP5MC1 against intramitochondrial proteolysis. In addition, binds the mitochondrial proton-transporting ATP synthase complexes I and may play a role in the stability of its membrane-bound subassemblies. |
| Protein Name | Transmembrane Protein 70 - Mitochondrial |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane ProteinMostly Located Within The Inner Cristae Membrane |
| Alternative Antibody Names | Anti-Transmembrane Protein 70 - Mitochondrial antibodyAnti-TMEM70 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
