| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TMOD1 (1-359) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:4000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TMOD1 |
| Gene ID: |
7111 |
| Uniprot ID: |
TMOD1_HUMAN |
| Immunogen Region: |
1-359 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-359 of human TMOD1 (NP_003266.1). |
| Immunogen Sequence: |
MSYRRELEKYRDLDEDEILG ALTEEELRTLENELDELDPD NALLPAGLRQKDQTTKAPTG PFKREELLDHLEKQAKEFKD REDLVPYTGEKRGKVWVPKQ KPLDPVLESVTLEPELEEAL ANASDAELCDIAAILGMHTL MSNQQYYQALSSSSIMNKEG LNSVIKPTQYKPVPDEEPNS TDVEETLERIKNNDPKLEEV NLNNIRNIPIPTLKAYAEAL KENSYVKKFSIVGTRSNDP |
| Tissue Specificity | Highly expressed in the erythrocyte, heart and skeletal muscle. |
| Function | Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus. |
| Protein Name | Tropomodulin-1Erythrocyte TropomodulinE-Tmod |
| Database Links | Reactome: R-HSA-390522 |
| Cellular Localisation | CytoplasmCytoskeletonIn Myofibrils With Sarcomeric StructureLocalizes To The Pointed End Of Actin Thin Filaments |
| Alternative Antibody Names | Anti-Tropomodulin-1 antibodyAnti-Erythrocyte Tropomodulin antibodyAnti-E-Tmod antibodyAnti-TMOD1 antibodyAnti-D9S57E antibodyAnti-TMOD antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
