| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TOB1 (1-140) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TOB1 |
| Gene ID: |
10140 |
| Uniprot ID: |
TOB1_HUMAN |
| Immunogen Region: |
1-140 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human TOB1 (NP_005740.1). |
| Immunogen Sequence: |
MQLEIQVALNFIISYLYNKL PRRRVNIFGEELERLLKKKY EGHWYPEKPYKGSGFRCIHI GEKVDPVIEQASKESGLDID DVRGNLPQDLSVWIDPFEVS YQIGEKGPVKVLYVDDNNEN GCELDKEIKNSFNPEAQVFM |
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Phosphorylated on Ser and Thr residues. |
| Function | Anti-proliferative protein.the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Mediates CPEB3-accelerated mRNA deadenylation by binding to CPEB3 and recruiting CNOT7 which leads to target mRNA deadenylation and decay. |
| Protein Name | Protein Tob1Transducer Of Erbb-2 1 |
| Cellular Localisation | CytoplasmNucleusOnly A Small Fraction Localizes To The Cytoplasm Except In Late S-Phase Where More Than Half Of Proteins Become Cytoplasmic |
| Alternative Antibody Names | Anti-Protein Tob1 antibodyAnti-Transducer Of Erbb-2 1 antibodyAnti-TOB1 antibodyAnti-TOB antibodyAnti-TROB1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
