Anti-Phospho-Dab1 (Y232) antibody

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Anti-Phospho-Dab1 (Y232) antibody

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Product name Anti-Phospho-Dab1 (Y232) antibody
Short Description Rabbit polyclonal against Phospho-Dab1 (Y232)
Description Rabbit polyclonal to Phospho-Dab1 (Y232).
Applications ELISA, IF, IHC, WB
Dilution range WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:20000
Specificity Phospho-Dab1 (Y232) Polyclonal Antibody detects endogenous levels of Dab1 protein only when phosphorylated at Y232.
Protein Name Disabled homolog 1
Immunogen Synthesized peptide derived from human Dab1 around the phosphorylation site of Y232.
Immunogen Region 170-250 aa
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Validated Application IHC
Host Rabbit
Clonality Polyclonal
Reactivity Avian, Human, Mouse, Rat
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 1600
Gene Symbol DAB1
Molecular Weight 60 kDa
Database Links HGNC:2661
Alternative Names Disabled homolog 1
Function Adapter molecule functioning in neural development. May regulate SIAH1 activity .
Post-translational Modifications Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons. Also phosphorylated on Ser-524 independently of reelin signaling.
Sequence and Domain Family The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.
Swiss-Prot Key O75553_HUMAN
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