Anti-CD3 antibody (FITC)

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Product name Anti-CD3 antibody (FITC)
Description Mouse monoclonal to CD3 (FITC).
Applications ELISA, IF
Dilution range IF 1:200-1:1000
ELISA 1:10000
Specificity CD3 Monoclonal Antibody-FITC labled detects endogenous levels of CD3 protein.
Protein Name T-cell surface glycoprotein CD3 zeta chain
T-cell receptor T3 zeta chain
CD antigen CD247
Immunogen Purified recombinant fragment of human CD3 expressed in E. Coli.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Validated Application FC IF
Host Mouse
Clonality Monoclonal
Clone ID 4D10A6
Reactivity Human
Conjugation FITC
Concentration 1 mg/ml
Purification Affinity purification
Isotype IgG2a
Formulation Purified antibody in PBS containing 0.03% sodium azide.
Gene ID 919
Gene Symbol CD247
Database Links HGNC:1677
OMIM:186780
Alternative Names T-cell surface glycoprotein CD3 zeta chain
T-cell receptor T3 zeta chain
CD antigen CD247
Function Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering.
Post-translational Modifications Phosphorylated on Tyr residues after T-cell receptor triggering.
Cellular Localization Membrane. Single-pass type I membrane protein.
Sequence and Domain Family The ITAM domains mediate interaction with SHB.
Swiss-Prot Key P20963_HUMAN
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