Anti-CD3 antibody (FITC)

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Product name Anti-CD3 antibody (FITC)
Description Mouse monoclonal to CD3 (FITC).
Applications ELISA, IF
Dilution range IF 1:200-1:1000
ELISA 1:10000
Specificity CD3 Monoclonal Antibody-FITC labled detects endogenous levels of CD3 protein.
Protein Name T-cell surface glycoprotein CD3 zeta chain
T-cell receptor T3 zeta chain
CD antigen CD247
Immunogen Purified recombinant fragment of human CD3 expressed in E. Coli.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Validated Application FC IF
Host Mouse
Clonality Monoclonal
Reactivity Human
Conjugation FITC
Concentration 1 mg/ml
Purification Affinity purification
Isotype IgG2a
Formulation Purified antibody in PBS containing 0.03% sodium azide.
Gene ID 919
Gene Symbol CD247
Database Links HGNC:1677
OMIM:186780
Alternative Names
T-cell surface glycoprotein CD3 zeta chain antibody
T-cell receptor T3 zeta chain antibody
CD antigen CD247 antibody
CD3Z antibody
T3Z antibody
TCRZ antibody
Function Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering.
Post-translational Modifications Phosphorylated on Tyr residues after T-cell receptor triggering.
Cellular Localization Membrane. Single-pass type I membrane protein.
Sequence and Domain Family The ITAM domains mediate interaction with SHB.
Swiss-Prot Key P20963_HUMAN
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