Anti-GFAP antibody

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Product name Anti-GFAP antibody
Short Description Rabbit monoclonal to GFAP
Description This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Applications IF, IHC, IP, WB
Dilution range WB 1:10000 - 1:50000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IP 1:20 - 1:50
Protein Name Glial fibrillary acidic protein
GFAP
Immunogen Recombinant protein of human GFAP
Storage Instruction Store at -20C. Avoid freeze / thaw cycles.
Note For Research Use Only (RUO).
Validated Application WB IHC IF IP
Host Rabbit
Clonality Monoclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene ID 2670
Gene Symbol GFAP
Molecular Weight 49.88 kDa
Database Links HGNC:4235
OMIM:137780
Reactome:R-HSA-1251985
Alternative Names Glial fibrillary acidic protein antibody
Function GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells
Post-translational Modifications Phosphorylated by PKN1,
Cellular Localization Cytoplasm,
Tissue Specificity Expressed in cells lacking fibronectin
Swiss-Prot Key P14136
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