Anti-GIT1 antibody

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Product name Anti-GIT1 antibody
Short Description Rabbit polyclonal to GIT1
Applications WB
Dilution range WB 1:200 - 1:2000
Protein Name ARF GTPase-activating protein GIT1
Cool-associated and tyrosine-phosphorylated protein 1
G protein-coupled receptor kinase-interactor 1
GRK-interacting protein 1
Immunogen Recombinant protein of human GIT1
Storage Instruction Store at -20C. Avoid freeze / thaw cycles.
Note For Research Use Only (RUO).
Validated Application WB
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene ID 28964
Gene Symbol GIT1
Molecular Weight 84.341 kDa
Database Links HGNC:4272
Alternative Names ARF GTPase-activating protein GIT1 antibody
ARF GAP GIT1 antibody
Cool-associated and tyrosine-phosphorylated protein 1 antibody
CAT-1 antibody
CAT1 antibody
G protein-coupled receptor kinase-interactor 1 antibody
GRK-interacting protein 1 antibody
Function GTPase-activating protein for the ADP ribosylation factor family, May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization, Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia, Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes, Involved in the regulation of cytokinesis
Post-translational Modifications Phosphorylated on tyrosine residues by PTK2/FAK1 and SRC in growing fibroblasts, Tyrosine-phosphorylation is increased following cell spreading on fibronectin, decreased in cells arrested in mitosis and increased in the ensuing G1 phase ,
Cellular Localization Cytoplasm,
Swiss-Prot Key Q9Y2X7
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